Highly efficient iron-catalyzed conjugate reduction of α,β-unsaturated ketones with polymethylhydrosiloxane

An iron-catalyzed ligand free conjugate reduction of α,β-unsaturated ketones with PMHS (polymethylhydrosiloxane) was reported to deliver the corresponding carbonyl compounds with up to 93% yield. This operationally simple protocol shows a broad substrate scope using readily available PMHS as a cost-effective and easy-to-handle reductive reagent.