Responses and tolerance mechanisms of microalgae to heavy metal stress: A review

Microalgae, the primary producers in water ecosystems, are the main food of fish and shrimp. Microalgae have a great capacity to absorb heavy metals, and low concentrations of heavy metals can promote the growth of them. But high concentrations have a strong influence on the physiological and biochemical processes in algae, such as growth, photosynthesis, cell ultrastructure, protein content and fatty acid composition. Heavy metals may also induce the formation of reactive oxygen species (ROS), which causes the oxidation damage of protein, lipid and thiol peptides, and activates the antioxidant system. Heavy metals can be removed or converted into another state by biosorption of cell surface, accumulation in cells, combining with antioxidant enzymes and so on. This review summarized the responses of microalgae to heavy metals and comprehensively described the removal and tolerance mechanisms by extracellular adsorption and intracellular accumulation, which are helpful to treat pollution and improve the culture of microalgae.