微泡
间充质干细胞
Wnt信号通路
脂肪组织
再生(生物学)
干细胞
再生医学
细胞
医学
干细胞疗法
癌症研究
生物信息学
细胞生物学
小RNA
生物
内科学
信号转导
生物化学
基因
遗传学
作者
Ramya Lakshmi Rajendran,Byeong‐Cheol Ahn,Prakash Gangadaran
标识
DOI:10.4252/wjsc.v17.i5.107078
摘要
Exosomes are derived from various cell types, including mesenchymal stem cells (MSCs), and play a crucial role in cellular communication, significantly influencing tissue repair and regeneration and facilitating the healing process. Thus, insights into the functions of exosomes present novel opportunities in regenerative therapy. This article aims to discuss the promising potential of exosomes derived from human adipose-derived MSCs in treating androgenetic alopecia. This study aims to highlight how exosomes derived from human adipose-derived MSCs enhance dermal papilla cell proliferation through the Wnt/β-catenin pathway, counteracting the effects of excessive dihydrotestosterone and offering a novel approach for treating androgenetic alopecia.
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