合成子
化学
环加成
烷基
催化作用
烯酮
立体化学
有机化学
作者
Bubul Das,Anjali Dahiya,Nilanjana Chakraborty,Bhisma K. Patel
出处
期刊:Organic Letters
[American Chemical Society]
日期:2023-07-06
卷期号:25 (28): 5209-5213
被引量:2
标识
DOI:10.1021/acs.orglett.3c01655
摘要
Elegant synthetic strategies for chromenopyrroles (azacoumestans) have been devised via cycloaddition of 2-hydroxychalcone/cyclic enones and alkyl isocyanoacetate, followed by lactonization. Herein, ethyl isocyanoacetate acts as a C–NH–C–C═O synthon contrary to its hitherto applications as a C–NH–C synthon. Subsequently, pentacyclic-fused pyrroles were also constructed from the o-iodo benzoyl chromenopyrroles using the Pd(II) catalyst.
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