Electrochemical determination of sulfaguanidine using COOH‐MWCNT coated GC electrode

Abstract The electrochemical behavior of sulfaguanidine was investigated in PBS buffer aqueous solutions. Cyclic voltammograms have shown that (1) the Sg provided a well‐defined irreversible oxidation peak (2) the signal‐to‐background current ratio is 3 times higher at COOH‐MWCNT coated GCE than that of bare GCE and (3) the modifying GCE surface by COOH‐MWCNT led to a significant improvement (2.7 folds) of the electrochemical response. It has been shown that Sg oxidizes according to a diffusion‐controlled mechanism. A linear calibration curve was obtained for the oxidation of Sg at 10–70 μM. The COOH‐MWCNT coated GCE has also been successfully used for the determination of Sg in real samples.