水杨醛
对映体
圆二色性
立体化学
真菌
衍生工具(金融)
细胞毒性T细胞
化学
绝对构型
生物
植物
体外
生物化学
金融经济学
经济
席夫碱
作者
Weimao Zhong,Yuchan Chen,Xiaoyi Wei,Junfeng Wang,Weimin Zhang,Fa‐Zuo Wang,Si Zhang
标识
DOI:10.1038/s41429-020-00395-x
摘要
Two pairs of new salicylaldehyde derivative enantiomers, salicylaldehydiums A and B (1 and 2), along with five known analogues were isolated and identified from a marine-derived fungus Eurotium sp. SCSIO F452. Their structures and absolute configuration were determined by extensive spectroscopic analysis and electronic circular dichroism (ECD) calculations. All the new optical pure enantiomers [(+)-1, (-)-1, (+)-2, (-)-2] were evaluated for their cytotoxic and antioxidative activities. Compound (-)-1 exhibited weak cytotoxic activity.
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