介孔材料
差示扫描量热法
化学工程
材料科学
傅里叶变换红外光谱
动态光散射
扫描电子显微镜
水溶液
透射电子显微镜
介孔二氧化硅
手性(物理)
吸附
解吸
核化学
化学
有机化学
纳米技术
纳米颗粒
催化作用
工程类
物理
复合材料
热力学
量子力学
手征对称破缺
Nambu–Jona Lasinio模型
夸克
作者
Gao Z,Xiaoqian Lv,Yu‐Fei Fu,Xianghuan Zang,Yongjun Sun,Shuo Li,Huimin Zhang,Shanlin Qiao,Long Wang,Yanping Sun
标识
DOI:10.1080/03639045.2020.1782421
摘要
Most of the mesoporous chiral mesoporous silica (CMS) was synthesized by the chiral surfactant-directing method. In this study, a facile method was designed to synthesize CMS. In this method, achiral amphiphile was used as templating agents, and dilute ammonia solution was applied to induce the chirality of the CMS. Meanwhile, its morphology can be controlled by changing the concentration of the aqueous ammonia solution. The obtained CMS was characterized by dynamic light scattering (DLS), X-ray diffraction (XRD), transmission electron microscopy (TEM), and scanning electron microscopy (SEM). The results showed that all of the CMS possessed highly ordered mesostructures, and as the concentration of ammonia decreases, the chirality of the CMS becomes more obvious. Water-insoluble drug curcumin (Cur) was used as a model drug. The characteristics of CMS before and after drug loading were further detected by Fourier transform infrared spectrometer (FT-IR), N2 adsorption–desorption and differential scanning calorimetry (DSC). The result showed that Cur was successfully loaded inside the pores of the CMS and remained an amorphous state due to steric inhibition. Additionally, CMS could significantly increase the release rate of Cur under different pH conditions.
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