Application of platelet-rich plasma in knee osteoarthritis

Objective To evaluate the clinical effects of platelet-rich plasma (PRP) injections in patients with knee osteoarthritis. Methods In our hospital diagnosed with 58 cases of knee osteoarthritis patients as the research object, in all patients of knee joint cavity are PRP injection treatment, once a week, each injection of 5 ml, total injection three times. After treatment were followed up regularly, through international general Marius Holm (Lysholm) score system of knee joint function evaluation of knee joint function of patients after treatment were scored. Results Among 58 cases and 116 knee joins, the first injection provided 5 patients and 10 knee joints with symptom relief. The twice injection relieved the symptoms of 25 patients and 50 knee joints. After the third injection; the symptoms of 45 patients and 90 knee joints were relieved. At 6 months after the treatment, 55 patients and 110 knee joints received symptom relief. The effective rate of treatment was 94.8%. 3 patients and 6 knee joints were reported with no symptom relief. Conclusion Intra-articular PRP injection for knee osteoarthritis is a valid treatment option. PRP might relieve the symptom of osteoarthritis (OA) patients in a short time, and have good treatment outcomes, especially in patients with a less degree of knee degeneration and younger age. Key words: Osteoarthritis; Platelet-rich plasma