Two Fatal Cases of Mixed Connective Tissue Disease: Description of Case Histories Terminating as Progressive Systemic Sclerosis

Two fatal cases of mixed connective tissue disease (MCTD) terminating as progressive systemic sclerosis are described clinically, serologically and pathologically. The prognosis of mixed connective tissue disease is probably more grave than that of systemic lupus erythematosus in spite of prednisone treatment.