医学
雄激素剥夺疗法
淋巴结
前列腺特异性抗原
谷氨酸羧肽酶Ⅱ
前列腺癌
抗原
前列腺
雄激素
睾酮(贴片)
泌尿科
PET-CT
肿瘤科
内科学
激素
癌症
正电子发射断层摄影术
核医学
免疫学
出处
期刊:Clinical Nuclear Medicine
[Ovid Technologies (Wolters Kluwer)]
日期:2022-02-17
卷期号:47 (7): 664-665
被引量:5
标识
DOI:10.1097/rlu.0000000000004107
摘要
Abstract A 72-year-old man with prostate cancer was found to have prostate-specific membrane antigen (PSMA)–avid oligometastasis on initial staging with 18 F-DCFPyL PET/CT. Meanwhile, his prostate-specific antigen was 10.0 ng/mL, and testosterone level was 381 ng/dL. Six weeks after initiation of treatment on androgen deprivation therapy plus abiraterone, his restaging 18 F-DCFPyL PET/CT showed decreased PSMA uptake in primary prostate lesion, but increased uptake in bone and lymph node metastases, whereas his prostate-specific antigen decreased to 0.7 ng/mL, and testosterone level was <3 ng/dL. This case illustrates hormone-sensitive metastatic bone and lymph node flare on 18 F-PSMA PET/CT.
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