作者
Liang Guo,Meng Xiao,Bin Cao,Fengli Qu,Yuliang Zhan,Yunjian Hu,Xinru Wang,Guowei Li,Hui Gu,Jun Qi,Hui Yuan,Rong Min,Feiyan Wang,Lin-Juan Liu,Haibin Wang,Wei Jiang,Xueguang Duan,Wei Xu,Yanhua Yu,Jianrong Su,Jianzhong Zhang,Jinqing Nong,Shumei Liu,Jun Li,Junting Liu,Zhigang Yue,Daizhi Yang,Jie Guo,Rui Zhao,Yanan Zhang,Xiaoyan Yang,Xiaoqing Liu,Po‐Ren Hsueh,Yingchun Xu
摘要
To investigate the species distribution and antifungal susceptibility profiles of yeast isolates causing invasive infections across Beijing.A total of 1201 yeast isolates recovered from blood and other sterile body fluids were correctly identified by matrix-assisted laser desorption/ionization TOF MS supplemented by DNA sequencing. Antifungal susceptibility testing was performed according to the Clinical and Laboratory Standards Institute broth microdilution method.Candida (95.5%) remained the most common yeast species isolated; Candida albicans (38.8%) and Candida parapsilosis (22.6%) were the leading species of candidemia. Azole resistances were mainly observed in Candida glabrata and Candida tropicalis isolates.This study outlined the epidemiologic data of invasive yeast infections and highlighted the need for continuous monitoring of azole resistances among C. glabrata and C. tropicalis isolates in Beijing.