次氯酸
化学
荧光
检出限
肉眼
光化学
滴定法
溶酶体
无机化学
生物化学
色谱法
光学
物理
酶
作者
Beibei Zhang,Xiaopeng Yang,Rui Zhang,Yao Liu,Xueling Ren,Ming Xian,Yong Ye,Yufen Zhao
出处
期刊:Analytical Chemistry
[American Chemical Society]
日期:2017-09-14
卷期号:89 (19): 10384-10390
被引量:192
标识
DOI:10.1021/acs.analchem.7b02361
摘要
A two-photon reversible fluorescent probe L1 was designed and synthesized. The fluorescence intensity of the probe solution was strong, while the fluorescence of the solution was obviously quenched and the color of the solution was changed after the addition of hypochlorous acid, indicating this is "naked-eye sensor" for the detection of HClO. The probe showed great selectivity for hypochlorous acid over other reactive oxygen species (ROS) and anions. Fluorescence titration experiments showed that the probe has a low detection limit of 0.674 μM. Because of a morpholine group introduced to the naphathalimide framework, probe L1 was successfully applied to detect intracellular HClO in lysosome.
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