光老化
皮肤老化
氧化应激
皮肤癌
药理学
医学
基质金属蛋白酶
皮肤病科
化学
传统医学
生物化学
癌症
内科学
作者
Miaomiao Ding,Wei Ling,Chun‐Yu Chen,Jiaping Chen,Changxiao Liu,Xin He
出处
期刊:PubMed
日期:2022-07-01
卷期号:47 (14): 3709-3717
被引量:1
标识
DOI:10.19540/j.cnki.cjcmm.20220415.601
摘要
Skin photoaging is exogenous aging caused by long-term ultraviolet radiation, which not only affects skin appearance, but also has a close relationship with the development of skin cancer. Saponins, flavonoids, polyphenols, polysaccharides, and extracts of Chinese medicine have been found to have anti-skin photoaging effects in recent studies. Various mechanisms such as anti-oxidative stress damage, inhibition of matrix metalloproteinase expression, promotion of collagen synthesis, inhibition of inflammatory response, DNA damage repair, enhancement of cell autophagy, and inhibition of melanin synthesis can improve the symptoms of skin photoaging and delay the photoaging process. With the active ingredients of Chinese medicine for anti-skin photoaging as the entry point, the study systematically discussed the research progress of the mechanisms underlying the anti-photoaging effects of active ingredients of Chinese medicine in recent years, in order to provide theoretical reference for the development of new anti-photoaging drugs and methods.
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