医学
尿失禁
科克伦图书馆
肥胖
减肥
腹部肥胖
促炎细胞因子
泌尿系统
内科学
梅德林
炎症
泌尿科
代谢综合征
荟萃分析
政治学
法学
作者
Stergios K. Doumouchtsis,Jemina Loganathan,Vasilios Pergialiotis
标识
DOI:10.1111/1471-0528.16848
摘要
Obesity prevalence is increasing worldwide, with significant healthcare implications. We searched PubMed/MEDLINE, Embase and the Cochrane Library for articles registered until June 2020 to explore the relationship between obesity and urinary (UI) and anal incontinence (AI). Obesity is associated with low-grade, systemic inflammation and proinflammatory cytokine release, producing reactive oxygen species and oxidative stress. This alters collagen metabolism and, in combination with increased intra-abdominal pressure, contributes to the development of UI. Whereas in AI, stool consistency may be a factor. Weight loss can reduce UI and should be a management focus; however, the effect of weight loss on AI is less clear.
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