纳米凝胶
超声
微乳液
卡拉胶
肿胀 的
Zeta电位
化学工程
材料科学
肺表面活性物质
悬挂(拓扑)
色谱法
化学
纳米技术
纳米颗粒
复合材料
药物输送
数学
生物化学
纯数学
工程类
同伦
作者
Sol Rodríguez,Fernando G. Torres,Junior Arroyo,Karen N. Gonzales,Omar P. Troncoso,Daniel López
标识
DOI:10.1177/2041247920960973
摘要
Novel carrageenan micro- and nanogels were developed via a sonication-assisted microemulsion processing route. The diameter of the dry samples ranged 197.3 −421.35 nm whereas the diameter of the samples suspended in water ranged 467.8–605.9 nm. Hybrid κ/ι-carrageenan, rather than κ- or ι-carrageenan was used for the first time for the preparation of micro- and nanogels. KCl was used as a cross-linking agent and Tween 80 was used as surfactant. The micro- and nanogels suspended in water were found to simultaneously exhibit a lower diameter, and a lower swelling ratio with higher Tween 80 content. The micro- and nanogel suspension yields a zeta potential value of −50.5 mV, superior to values reported elsewhere for pure κ- or ι-carrageenan micro- and nanogels. The high stability was attributed to the high hydrophile-lipophile balance (HLB = 15) value of Tween 80. These results suggest that hybrid κ/ι-carrageenan micro- and nanogels are promising candidates for smart therapeutics applications.
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