Two novel spermidine alkaloids from the roots of Capparis acutifolia

Acutifoline A and Acutifoline B (C1 and C2, respectively) are two novel spermidine alkaloids obtained from Capparis acutifolia roots. The structures of the novel compounds were determined through extensive spectroscopic methods, such as 1D and 2D nuclear magnetic resonance spectroscopy and high resolution-electrospray ionization-mass spectroscopy (HR-ESI-MS). In addition, the anti-rheumatoid arthritis activities of the compounds were evaluated.