遗传增强
听力学
听力损失
医学
基因
遗传学
生物
助听器
感音神经性聋
生物信息学
作者
Vassili Valayannopoulos,Manohar Bance,Daniela Carvalho,John H. Greinwald,Steven Harvey,Akira Ishiyama,Evie C. Landry,Hubert Löwenheim,Lawrence R. Lustig,Manuel Manrique,Robert Nash,Rubén Polo,Cedric V. Pritchett,Jay T. Rubinstein,A. Eliot Shearer,Ignacio del Castillo,Jeffery J. Anderson,C. Eduardo Corrales,Tera Quigley,William J. Riggs
标识
DOI：10.1056/nejmoa2400521
摘要
DB-OTO gene therapy improved hearing in patients with OTOF-related deafness, enabling natural acoustic hearing and normalizing hearing sensitivity in 3 of 12 treated patients. (Funded by Regeneron Pharmaceuticals; ClinicalTrials.gov number, NCT05788536.).
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(2025-6-4)
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