医学
列线图
乳腺癌
肿瘤科
内科学
比例危险模型
肿块切除术
乳房切除术
淋巴结
癌症
妇科
作者
Fei Lin,Wen Xia,Miao Chen,Ting Jiang,Jia Guo,Yu Ouyang,Haohui Sun,Xiaoyu Chen,Wuguo Deng,Ling Guo,Huan‐Xin Lin
出处
期刊:Nutrients
[MDPI AG]
日期:2022-09-14
卷期号:14 (18): 3783-3783
被引量:4
摘要
The nutritional risk index (NRI) is an independent prognostic factor for overall survival in various cancers, but its prognostic value in breast cancer remains unclear. This study aimed to explore the relationship between the NRI and overall survival (OS) in breast cancer and to develop a predictive nomogram.We retrospectively enrolled 1347 breast cancer patients who underwent mastectomy or lumpectomy between January 2011 and November 2012. Using a cutoff value of 110.59, patients were divided into a high-NRI group and a low-NRI group. OS was compared between the two groups. Clinicopathological factors independently associated with survival were used to construct a predictive nomogram.Of the 1347 patients, 534 patients were classified as high NRI and 813 as low NRI. OS was significantly shorter in low-NRI patients. The 3- and 5-year OS rates were 87.3% and 73.4%, respectively, in the high-NRI group whereas they were 83.0% and 67.2%, respectively, in the low-NRI group. Cox regression analysis found that histopathological type, tumor size, lymph node status, progesterone receptor (PR) status, Ki-67, and NRI were independently associated with OS.NRI is an independent prognostic factor of OS in breast cancer patients. The proposed nomogram model may be a useful tool for individualized survival prediction.
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