In this study,the antioxidant activities of hericium erinaceus polysaccharides,lentinan,tremella polysaccharides,grifolan,coprinus comatus polysaccharides and their compound polysaccharides in vitro were examined.It was found that these polysaccharides(0.5 mg·mL-1) all had been shown to display significantly antioxidant properties,decreased not(1,1-diphenyl-2-picrylhydrazyl radicals and hydroxyl radicals,but also superoxide anion ridicals with different degrees.These results clearly suggested that these polysaccharides were bioactive agents having significant antioxidant actions,and the compound use of these polysaccharides had better antioxidant effects,grifolan showed the best antioxidant activity and was able to reduce radicals in(89.5±1.3)%,(62.4±0.6)%,(47.9±1.0)%,respectively.