化学
溴
氯
SN2反应
结构异构体
氯化物
药物化学
离子键合
双键
有机化学
离子
作者
Ilpo O.O. Korhonen,Maija Pitkänen,Jorma Korvola
出处
期刊:Tetrahedron
[Elsevier]
日期:1982-01-01
卷期号:38 (18): 2837-2841
被引量:11
标识
DOI:10.1016/0040-4020(82)85011-4
摘要
The additions of chlorine, bromine and bromine chloride to trans methyl 2-butenoate 1, trans methyl 2-methyl-2-butenoate 2 and methyl 3-methyl-2-butenoate 3 under ionic conditions were studied. Bromine chloride addition always gave as a major regioisomer the 2-bromo-3--chloro compound,almost quantitatively in the case of 3. The mechanism of bromonium ion ring-opening (SN1 or SN2) is discussed with respect to the double bond substitution and regioisomer proportions. The dihalo products were identified by MS, 1H and 13C NMR.
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