A new coumarin-based “turn-on” fluorescence probe with high sensitivity and specificity for detecting hypochlorite ion

A new type of “turn-on” fluorescence probe coumarin-based DTC was developed for specifically detecting hypochlorite ion (ClO−) with high sensitivity. DTC can display a significant enhancement of fluorescence and emit blue fluorescence at 452 nm after reaction with ClO−. Moreover, probe DTC can detect ClO− without interference from other reactive oxygen species (ROS), and has a low detection limit for ClO− of 96 nM. Meanwhile, DTC can also detect ClO− in the physiological environment, and DTC can be further used as a test paper-strip for portable and rapid detection of ClO−.