Targeting mutant p53 with PK11007: A new approach for the treatment of patients with triple-negative breast cancer?
癌症研究
癌症
突变
作者
Naoise C Synnott,Matthias R Bauer,Stephen F. Madden,Alyson Murray,Rut Klinger,Norma O'Donovan,Darran P. O'Connor,William M. Gallagher,John Crown,Alan R. Fersht,Michael J. Duffy
e14099Background:The identification of a targeted therapy for patients with triple-negative breast cancer (TNBC) is one of the most urgent needs in breast cancer therapeutics. Since the p53 gene is...