有丝分裂
细胞生物学
生物
核心
细胞分裂
主轴装置
细胞
遗传学
作者
Daniel Moreno-Andrés,Kristin Holl,Wolfram Antonin
标识
DOI:10.1016/j.semcancer.2022.11.013
摘要
The nucleus undergoes dramatic structural and functional changes during cell division. With the entry into mitosis, in human cells the nuclear envelope breaks down, chromosomes rearrange into rod-like structures which are collected and segregated by the spindle apparatus. While these processes in the first half of mitosis have been intensively studied, much less is known about the second half of mitosis, when a functional nucleus reforms in each of the emerging cells. Here we review our current understanding of mitotic exit and nuclear reformation with spotlights on the links to cancer biology.
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