Hickam versus Ockham: atopic dermatitis and bullous pemphigoid or pemphigoid nodularis? Dupilumab solves the problem

From a diagnostic point of view, the case presented raises a dilemma, in fact, it is not possible to state with certainty whether the patient described suffered from pemphigoid nodularis or from concomitance of atopic dermatitis prurigo nodularis-like and bullous pemphigoid. In spite of this diagnostic dilemma, our findings support the use of dupilumab in atopic dermatitis prurigo nodularis-like, bullous pemphigoid and pemphigoid nodularis, especially in treating pruritus.