Electrochemical sensor based on MOF derived LaFexNi(1-x)O3 using carbon spheres as the template for simultaneous determination of p-aminophenol and paracetamol

Using metal–organic frameworks (MOFs) as the precursor and carbon spheres as the template, LaFexNi(1-x)O3 (x = 1, 0.8, 0.6, 0.4, 0.2, 0) perovskite-type oxides were synthesized. The structure, morphology and valence state of as-prepared perovskite-type oxides were characterized by X-ray diffraction, scanning electron microscope, transmission electron microscopy, and X-ray photoelectron spectroscopy. Cyclic voltammetry and electrochemical impedance techniques were used to study the effect of Ni-doping ratios on the electrocatalytic performance of perovskite. The differential pulse voltammetry was used to measure the content of p-aminophenol (PAP) and paracetamol (PAT) through the LaFe0.6Ni0.4O3 modified glassy carbon electrode. The experiment shows that among LaFexNi(1-x)O3 (x = 1, 0.8, 0.6, 0.4, 0.2, 0) perovskite-type oxides, LaFe0.6Ni0.4O3 was best electrode material due to its low charge transfer resistance and high electrochemical active surface area. The linear ranges of PAP and PAT were both 1.0–100.0 μM under optimized conditions, while the detection limits were 0.111 and 0.162 μM (S/N = 3), respectively. The practicality of the suggested sensor was explored through the simultaneous detection of PAP and PAT in real samples, and satisfactory findings in acetaminophen pills were obtained.