Bone Marrow Stromal Cells Promote Osteogenic Differentiation and Induce Bone Remodeling and Healing in Osteoporosis.

Collectively, miR-17 delivered by BMSC exosomes promotes osteogenic differentiation and induces bone healing in osteoporosis through BARX2 regulation. The combined use of exosome inhibitors confirmed the therapeutic effect of BMSCs and BMSC exosomes containing miRNAs on various diseases.