拉明
表型
磁共振成像
心脏病学
医学
内科学
核磁共振
疾病
物理
遗传学
生物
放射科
基因
精神科
核心
作者
Constantin‐Cristian Topriceanu,Mashael Alfarih,George Joy,Fiona Chan,Matt Webber,Denis C. Ilie-Ablachim,Hunain Shiwani,Migma Dorji Tamang,Catherine M. Banks,Stephen Pettit,Steffen E. Petersen,Benjamin O’Brien,Alun D. Hughes,Iain Pierce,William E. Moody,Richard P. Steeds,Paolo Emilio Puddu,Peter Kellman,Konstantinos Savvatis,Saidi Mohiddin
标识
DOI：10.1016/j.jcmg.2025.01.004
摘要
The CMR phenotype of LMNA carriers with preserved left ventricular systolic function consists of longer T2, higher serum troponin levels, higher extracellular volume, and impaired strain. CMR-derived focal fibrosis and strain biomarkers are prognostic, and future studies should explore their added clinical utility beyond the currently available MACE risk prediction tools. (The Deep Phenotype of Lamin A/C Cardiomyopathy; NCT03860454).
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(2025-6-4)
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