Image Analysis as tool for Predicting Colorectal Cancer Molecular Alterations: A Scoping Review

This scoping review underscores the potential of radiogenomics in predicting molecular alterations in colorectal cancer through non-invasive imaging modalities, like CT, MRI, and ¹⁸F-FDG PET/CT. The analysis of 41 studies showed the appropriate prediction of key alterations, such as KRAS, NRAS, BRAF, TP53, and MSI, highlighting the promise of radionics and texture features in enhancing predictive accuracy.