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Pain in High-Dose-Rate Brachytherapy for Cervical Cancer: A Retrospective Cohort Study

医学 止痛药 曲马多 安乃近 麻醉 回顾性队列研究 癌症疼痛 近距离放射治疗 入射(几何) 外科 癌症 放射治疗 内科学 物理 光学
作者
Ángel Ignacio Lledó Becerra,Miriam Jiménez-Gil,Mario Federico,Yurena Domínguez-Díaz,Lucía Valencia,Aurelio Rodríguez
出处
期刊:Journal of Personalized Medicine [Multidisciplinary Digital Publishing Institute]
卷期号:13 (8): 1187-1187 被引量:2
标识
DOI:10.3390/jpm13081187
摘要

High-dose-rate brachytherapy (HDR) is part of the main treatment for locally advanced uterine cervical cancer. Our aim was to evaluate the incidence and intensity of pain and patients' satisfaction during HDR. Risk factors for suffering pain were also analyzed. A retrospective study was carried out by extracting data from patients who had received HDR treatment for five years. Postoperative analgesia had been administered using pre-established analgesic protocols for 48 h. Pain assessment was collected according to a protocol by the acute pain unit. Analgesic assessment was compared according to analgesic protocol administered, number of needles implanted, and type of anesthesia performed during the procedure. From 172 patients treated, data from 247 treatments were analyzed. Pain was considered moderate in 18.2% of the patients, and 43.3% of the patients required at least one analgesic rescue. Patients receiving major opioids reported worse pain control. No differences were found regarding the analgesic management according to the intraprocedural anesthesia used or the patients' characteristics. The number of inserted needles did not influence the postoperative analgesic assessment. Continuous intravenous infusion of tramadol and metamizole made peri-procedural pain during HDR mild in most cases. Many patients still suffered from moderate pain.
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