败血症
体温过低
医学
重症监护医学
心动过速
随机对照试验
麻醉
内科学
作者
Marc Doman,Michaël Thy,Julien Dessajan,Mariem Dlela,Hermann Do Rego,Erwann Cariou,Michael Ejzenberg,Lila Bouadma,Étienne de Montmollin,Jean‐François Timsit
标识
DOI:10.3389/fmed.2023.1292468
摘要
Fever can be viewed as an adaptive response to infection. Temperature control in sepsis is aimed at preventing potential harms associated with high temperature (tachycardia, vasodilation, electrolyte and water loss) and therapeutic hypothermia may be aimed at slowing metabolic activities and protecting organs from inflammation. Although high fever (>39.5°C) control is usually performed in critically ill patients, available cohorts and randomized controlled trials do not support its use to improve sepsis prognosis. Finally, both spontaneous and therapeutic hypothermia are associated with poor outcomes in sepsis.
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