Synthetic strategies for thiazolopyridine derivatives

AbstractBoth thiazole and pyridine are well recognized heterocycles. The fusion of these two heterocycles results in thiazolopyridine ring system, which is the part of a large number of natural and synthetic products. Thiazolopyridine derivatives have significant biological and pharmaceutical importance such as anti-hypertensive, anti-oxidant, anti-fungal, anti-cancer, anti-mitotic, anti-microbial, anti-diabetic, analgesic, tuberculostatic and herbicidal. Various thiazolopyridine derivatives have found their applications in semiconductor and photographic materials. A large variety of synthetic methods have been employed for the facile synthesis of thiazolopyridine derivatives. This review article focuses on the synthesis of five isomeric thiazolopyridine systems.Keywords: Thiazolo[32-a]pyridinesThiazolo[45-b]pyridineThiazolo[54-b]pyridineThiazolo[54-c]pyridinesThiazolo[45-c]pyridine Additional informationFundingThis work was supported by the Higher Education Commission of Pakistan, Government College University, Faisalabad, Pakistan.