2019年冠状病毒病(COVID-19)
大流行
医学
纳米医学
鼻腔给药
严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)
重症监护医学
2019-20冠状病毒爆发
冠状病毒
病毒学
纳米技术
爆发
疾病
传染病(医学专业)
内科学
材料科学
纳米颗粒
作者
Bin Tu,Yankun Gao,Xinran An,Huiyuan Wang,Yongzhuo Huang
标识
DOI:10.1016/j.apsb.2022.09.011
摘要
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has been a major health burden in the world. So far, many strategies have been investigated to control the spread of COVID-19, including social distancing, disinfection protocols, vaccines, and antiviral treatments. Despite the significant achievement, due to the constantly emerging new variants, COVID-19 is still a great challenge to the global healthcare system. It is an urgent demand for the development of new therapeutics and technologies for containing the wild spread of SARS-CoV-2. Inhaled administration is useful for the treatment of lung and respiratory diseases, and enables the drugs to reach the site of action directly with benefits of decreased dose, improved safety, and enhanced patient compliance. Nanotechnology has been extensively applied in the prevention and treatment of COVID-19. In this review, the inhaled nanomedicines and antibodies, as well as intranasal nanodrugs, for the prevention and treatment of COVID-19 are summarized.
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