化学
席夫碱
取代基
三嗪
1,3,5-三嗪
碳-13核磁共振
元素分析
质子核磁共振
基础(拓扑)
组合化学
光化学
结晶学
高分子化学
有机化学
数学分析
数学
作者
Ayman El‐Faham,Saied M. Soliman,Hazem A. Ghabbour,Yasser A. Elnakady,Talal A. Mohaya,Mohammed Rafiq H. Siddiqui,Fernando Alberício
标识
DOI:10.1016/j.molstruc.2016.06.061
摘要
Novel series of s-triazine-Schiff base derivatives were synthesized employing ultrasonic irradiation and characterized by NMR (1H and 13C), FT-IR, and elemental analysis. The use of ultrasonic irradiation has allowed the preparation of the target products with better yields in shorter reaction time and excellent purities compared to the conventional heating. X-ray single crystal diffraction experiments verified the molecular structure of four from the new prepared s-triaizne-Schiff base derivatives. The molecular structures of the studied compounds are computerized using DFT/B3LYP method. The effects of substituent at the triazine and phenyl ring on the electronic and spectroscopic properties of the studied compounds were also investigated. The natural atomic charges showed that pipridino-s-triazine derivatives are richer in electrons than those having morpholino derivatives. The anti-proliferative effects for the prepared compounds were tested against three different cancer cell lines.
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