Expression and diagnostic value of HE4 level in early serous ovarian

Objective: To discuss the expression and diagnostic value of HE4 level in early serous ovarian cancer.Methods: HE4 and CA125 of 43 patients with serous ovarian cancer,43 patients with benign ovarian diseases and 43 health people were detected and compared.Results: HE4 and CA125 of patients with serous ovarian cancer were significantly higher than the other two groups(P0.05);and the positive rate of HE4 were significantly higher than CA125 in patients with serous ovarian cancer(P0.05).Conclusions: HE4 and CA125 showed a significantly increased expression in ovarian cancer patients,but HE4 is more sensitive in early diagnosis of serous ovarian cancer.