Mechanisms of TKI-induced diarrhea in cancer patients.
胃肠病学
癌症研究
作者
Joanne M. Bowen
出处
期刊:Current Opinion in Supportive and Palliative Care [Ovid Technologies (Wolters Kluwer)] 日期:2013-06-01卷期号:7 (2): 162-167被引量:38
标识
DOI:10.1097/spc.0b013e32835ec861
摘要
Purpose of reviewTyrosine kinase inhibitors (TKIs) are increasingly common treatments for cancer; however, their effective use is hampered by unwanted side effects. One of the most common of these is TKI-induced diarrhea, although so far very little is known about its mechanisms and the best managem