Impact of azathioprine on the prevention of postoperative Crohnʼs disease recurrence: Results of a prospective, observational, long-term follow-up study

Early postoperative use of AZA seems to delay EPR development in comparison to historical series or placebo groups in randomized controlled trials. Although usually considered as endoscopic recurrence, those lesions confined to the ileocolonic anastomosis are not likely to progress or to become symptomatic in the short term.