瞬时受体电位通道
感觉
感觉系统
TRPM8型
热感受器
神经科学
离子通道
生物
化学
受体
遗传学
TRPV1型
作者
Ardem Patapoutian,Andrea Peier,Gina M. Story,Veena Viswanath
摘要
We possess an acute sense of temperature. Most of us seek shade on a hot summer day, prefer a warm shower to a cold one, and enjoy red wines served at a temperature of 15–18°C. Thermosensation not only affects our comfort, but is also essential for the survival of most organisms. We are now beginning to uncover the molecular identity of proteins that confer thermosensation. The thermoTRPs, a subset of transient receptor potential ion channels are activated by distinct physiological temperatures, and are involved in converting thermal information into chemical and electrical signals within the sensory nervous system.
科研通智能强力驱动
Strongly Powered by AbleSci AI