[Objective] To study the antioxidant activity of the mixture solution of Cordyceps militaris extracts and different proportions of extracts from LUCID GANODERMA,LENTINULA,HERICIUM,FOLIUM PERILLAE and FOLIUM GINKGO.[Method] The extracts were prepared by microwave method,one,two or three of the extracts from LUCID GANODERMA,LENTINULA,HERICIUM,FOLIUM PERILLAE and FOLIUM GINKGO were mixed with Cordyceps militaris extracts at certain proportions,and then the total reducing capacity and ·OH scavenging capacity of the mixture solution were determined and compared with that of single extract.[Result] The mixture solution of Cordyceps militaris extracts A,FOLIUM PERILLAE extracts E and FOLIUM PERILLAE extracts F had better antioxidant activity,and the antioxidant activity of other mixture solutions all improved to different extents compared with the single extract.[Conclusion] The mixed solution of edible-medicinal fungi extracts and medicinal plants extracts showed higher antioxidant activity,and the antioxidant activity of most mixture solution was better than that of single extract.