There have been great development on concepts,forms of exporessions,epidemiology,standards of diagnosis,prevention and controlling measures of sub-health state at home and abroad in recent years.While it is not uniform such as fatigue of sub-health state and standards of diagnosis.So,the key of study on fatigue state of sub-health state is to set the testing standard of sub-health state.This article summaries the current study of fatigue state of sub-health state recent years.