医学
妊娠胆汁淤积症
怀孕
妊娠期糖尿病
产科
高脂血症
体质指数
胆汁淤积
糖尿病
入射(几何)
妊娠期
胎儿
内科学
内分泌学
物理
光学
生物
遗传学
作者
Ping Li,Yurong Jiang,Mina Xie,Yu You
出处
期刊:Medicine
[Ovid Technologies (Wolters Kluwer)]
日期:2023-01-06
卷期号:102 (1): e32586-e32586
被引量:2
标识
DOI:10.1097/md.0000000000032586
摘要
The aim of this study was to investigate the clinical features and risk factors of intrahepatic cholestasis of pregnancy (ICP) and its effect on pregnancy outcomes. The data from 300 pregnant women with ICP and 300 pregnant women without ICP admitted from July 2015 to December 2016 at Changsha Maternal and Child Health Hospital were collected. The factors associated with ICP were examined. The family history of ICP, twin pregnancies, number of births, hypertensive disorder of pregnancy (HDP), gestational diabetes, hyperlipidemia, hepatitis virus infection, and in vitro fertilization and embryo transfer, differed significantly between the 2 groups (all P < .05). The multivariable analysis showed that body mass index at delivery, number of births, HDP, gestational diabetes, hyperlipidemia, and hepatitis virus infection were associated with ICP (all P < .05). The incidence of abnormal amniotic fluid and premature births in the ICP group were significantly higher than in the control group (all P < .05). ICP is associated with BMI at delivery, number of births, HDP, gestational diabetes, hyperlipidemia, and hepatitis virus infection. ICP greatly influences pregnancy outcomes.
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