Targeting Alzheimer’s disease pathology: influence of nano-based drug delivery systems loaded with a combination of herbal and synthetic drugs

Current treatments mainly offer early symptomatic relief but fail to target multiple neurobiological mechanisms of AD. Combining established therapies with herbal drugs can enhance efficacy and reduce side effects. Co-loading synthetic drugs and phytoconstituents in one nanoformulation can improve targeted delivery, sustained release, and minimize systemic effects for better outcomes.