硅烷
烯烃
化学
催化作用
杂原子
金属
光化学
氧化还原
有机化学
组合化学
药物化学
烷基
硅烷
作者
Jing Hou,Aloysius Ee,Helin Cao,Han Wee Ong,Jinhui Xu,Jie Wu
标识
DOI:10.1002/anie.201811266
摘要
Catalytic alkene difunctionalization via Si-H and C-H activations represents an ideal atom- and step-economic pathway for quick assembly of molecular complexity. We herein developed a visible-light-promoted metal-free difunctionalization of alkenes using abundant CO2 and readily available Si-H and C(sp3 )-H bonds as feedstocks. Through the merger of photoredox and hydrogen-atom-transfer catalysis, a variety of value-added compounds, such as β-silacarboxylic acids and acids bearing a γ-heteroatom (e.g., N, O, S) could be directly accessed from simple alkenes in a redox-neutral fashion.
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