医学
食物过敏
口服免疫疗法
过敏
鸡蛋过敏
生活质量(医疗保健)
儿科
人口统计学的
特应性皮炎
免疫学
人口学
社会学
护理部
作者
Naama Epstein‐Rigbi,Naama Schwartz,Michael R. Goldberg,Michael B. Levy,Liat Nachshon,Arnon Elizur
摘要
Abstract Background The start of oral immunotherapy (OIT) for food allergy is a critical period in the treatment process, with a potential to influence patient quality of life (QOL) and subsequently treatment outcome. The association of medical clowning with QOL at OIT initiation was examined. Methods Children aged 4‐12 years supported by a medical clown (MC) during the induction week of OIT for food allergy were studied. Children in the same age range starting OIT without the support of a MC served as controls. Parents of all children completed the Food Allergy Quality of Life Questionnaire—Parent Form (FAQLQ‐PF), and children aged 8‐12 years completed the Food Allergy Quality of Life Questionnaire—Child Form (FAQLQ‐CF). QOL scores of parents and children with and without a MC support were compared. Results Children with (n = 88) and without (n = 212) the support of a MC were comparable in demographics and clinical characteristics. The study group had a significantly lower single highest tolerated dose compared to controls (57 ± 83 vs 162 ± 274 mg protein, respectively, P < .001). Parental perception of the QOL of children was not associated with a MC support ( P = .81) but rather with previous reaction severity ( P < .01). In contrast, the QOL of children aged 8‐12 years (n = 119) was positively associated primarily with a MC support, total score 3.7 ± 1.1 vs 4.6 ± 1.3 ( P < .001). Conclusions While the perception of QOL of parents of children with food allergy at OIT initiation is mainly associated with previous reaction severity, the QOL of the children themselves is primarily positively associated with MC support.
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