赭曲霉毒素A
纳米技术
表面增强拉曼光谱
适体
胶体金
纳米传感器
纳米材料
拉曼光谱
化学
材料科学
纳米颗粒
真菌毒素
拉曼散射
生物
光学
物理
食品科学
遗传学
作者
Yulán Hernández,Lesly K. Lagos,Betty C. Galarreta
标识
DOI:10.1016/j.sbsr.2020.100331
摘要
Nanomaterials use in traditional spectroscopic assays has enabled the development of more sensitive and accessible methods with wider-range of applications. Usually, the sensitivity of nanosensors is improved through the incorporation of labels or by inducing nanoparticles aggregation. Herein, we present the development of a label-free, selective, reliable, and affordable gold nanoprisms aptasensor to detect the content of ochratoxin A (OTA) in suspension by surface-enhanced Raman spectroscopy (SERS). Label-free SERS provides a molecular signature of the aptamer-OTA complex used and enables to discriminate OTA solutions from 10 to 250 ppb (25–620 nM) with multivariate analysis. This label-free nanoaptasensing system represents a new possibility for simpler and more reliable and accessible procedures for OTA determination.
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