The immune effect of radiotherapy on tumor

Recently, immunologists have payed the attention to the effects of ionizing radiation on tumor immunity, and attempted to induce and improve anti-tumor immune effects with it. More and more evidences showed that exact radiotherapy scheme and irradiation dose, particularly combined with immunotherapy, could induce or regulate systemic immune response and contributed to tumor control and inflammatory occurrence. This paper reviewed the effects and mechanisms of radiotherapy on tumor immune and the results in combination with immunotherapy here for guiding the effective combined application of radiotherapy and immunotherapy. Key words: Tumor; Radiotherapy; Immunotherapy; Immune response