怀孕
贫血
胎龄
胎儿
缺铁
宫内生长受限
小于胎龄
血红蛋白
铁蛋白
作者
Lotta Kemppinen,Mirjami M. Mattila,Eeva Ekholm,Nanneli Pallasmaa,Ari Törmä,Leila Varakas,Kaarin Mäkikallio
出处
期刊:Journal of Perinatal Medicine
[De Gruyter]
日期:2021-05-01
卷期号:49 (4): 431-438
被引量:5
标识
DOI:10.1515/jpm-2020-0379
摘要
OBJECTIVES Gestational IDA has been linked to adverse maternal and neonatal outcomes, but the impact of iron supplementation on outcome measures remains unclear. Our objective was to assess the effects of gestational IDA on pregnancy outcomes and compare outcomes in pregnancies treated with either oral or intravenous iron supplementation. METHODS We evaluated maternal and neonatal outcomes in 215 pregnancies complicated with gestational IDA (Hb<100 g/L) and delivered in our tertiary unit between January 2016 and October 2018. All pregnancies from the same period served as a reference group (n=11,545). 163 anemic mothers received oral iron supplementation, and 52 mothers received intravenous iron supplementation. RESULTS Gestational IDA was associated with an increased risk of preterm birth (10.2% vs. 6.1%, p=0.009) and fetal growth restriction (FGR) (1.9% vs. 0.3%, p=0.006). The gestational IDA group that received intravenous iron supplementation had a greater increase in Hb levels compared to those who received oral medication (18.0 g/L vs. 10.0 g/L, p<0.001), but no statistically significant differences in maternal and neonatal outcomes were detected. CONCLUSIONS Compared to the reference group, prematurity, FGR, postpartum infections, and extended hospital stays were more common among mothers with gestational IDA, causing an additional burden on the families and the healthcare system.
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