肌内脂肪
生物
小桶
候选基因
脂肪组织
RNA序列
遗传学
繁殖
转录组
基因
基因表达
动物科学
内分泌学
作者
Xuemei Yang,Yan Liang,Zhijun Zhong,Xuan Tao,Yuekui Yang,P. Zhang,Y. Wang,Lei Ye,X.‐H. Chen,Kai Zeng,Jing Gong,Sancheng Ying,J.‐L. Zhang,Jianhui Pang,Xuebin Lv,Yiren Gu,Zhiping He
摘要
Summary lncRNAs play crucial roles in fat metabolism in animals. Previously, we have compared the mRNA transcriptome profiles between seven fat‐type Chinese pig breeds and one lean‐type Western breed (Yorkshire, YY). The associations between differentially expressed (DE) genes and phenotypical traits were investigated. In the present study, to further explore the underlying regulatory mechanisms, lncRNAs were sequenced and compared between YY and Chinese indigenous breeds. The results showed 9114 and 7538 DE lncRNAs between at least one Chinese breed and the YY breed in the adipose and muscle tissue respectively. KEGG enrichment analysis revealed that the target genes of these DE lncRNAs mainly influenced the glucolipid metabolism, which is an important process affecting meat quality. Correlation analyses between the DE lncRNA and DE mRNA genes related to meat quality and growth traits were performed. The results showed that LTCONS_00073280 was associated with intramuscular fat content. Four lncRNAs (LTCONS_00101781, LTCONS_00037879, LTCONS_00088260 and LTCONS‐00128343) might mediate backfat thickness. Overall, this study provides candidate lncRNAs that potentially affect meat quality, which might be useful for molecular breeding of pig breeds in future.
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