化学
硝基
多米诺骨牌
桂皮酸盐类
烯丙基重排
非对映体
有机化学
共轭体系
组合化学
催化作用
聚合物
烷基
作者
Stefania Fioravanti,Lucio Pellacani,Maria Cecilia Vergari
摘要
Efficient one-pot methods for the synthesis of variously functionalised conjugated nitro alkenes have been reported. Despite the utility in different fields of these compounds, only a few multi-step syntheses have been reported in the literature, giving the target compounds in low overall yields. α-Nitro acrylates or cinnamates, α-nitro α,β-unsaturated ketones and, most importantly, aromatic and heteroaromatic (E)- 2-nitro allylic alcohols, compounds characterised by a well-known anticancer activity, were obtained in high yields and high diastereomeric purity by a domino condensation-dehydration process.
科研通智能强力驱动
Strongly Powered by AbleSci AI