生物膜
支架
粪肠球菌
体内
医学
细菌
微生物学
泌尿系统
抗生素
变形杆菌
化学
外科
生物
内科学
大肠杆菌
金黄色葡萄球菌
生物化学
生物技术
基因
遗传学
作者
Patrick F. Keane,Michael Bonner,S. R. Johnston,Atif Zafar,Seán Gorman
出处
期刊:British journal of urology
[Wiley]
日期:1994-06-01
卷期号:73 (6): 687-691
被引量:148
标识
DOI:10.1111/j.1464-410x.1994.tb07557.x
摘要
Objective To examine the relationship between encrustation and microbial biofilm formation on indwelling ureteric stents. Patients and methods Ureteric stents from 40 patients were examined for the presence of a microbial biofilm and encrustations. Bacteria in stent biofilms were isolated and identified. Results A profuse biofilm (> 10 4 c.f.u. cm 3–3 ) was identified on 1J (28%) stents. Enterococcus faecalis was the most common biofilm organism identified and Proteus spp. were not present. Encrustation was seen in 23 (58%) of stents and was not associated with the level of urinary calcium. The major risk factor for stent encrustation was the presence of urolithiasis. Importantly, there was no causative link between stent biofilm formation and encrustation. Both biofilm formation and encrustation increased with the duration of stenting. Conclusion The results indicate that polyurethane is readily encrusted and colonized by bacteria in vivo despite antibiotic prophylaxis. Newer materials must be sought if effective long‐term stenting is to be achieved.
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