Familial Exudative Vitreoretinopathy Associated With Nonneovascular Chronic Angle-Closure Glaucoma

Purpose Cases of angle-closure glaucoma in patients with familial exudative vitreoretinopathy have been reported secondary to neovascularization of the anterior segment. Cases secondary to nonneovascular mechanisms have not been previously reported. Methods Two cases are presented of angle-closure glaucoma as a result of a nonneovascular mechanism. Results Neovascularization was found to be a very unlikely explanation for the angle closure in these two cases. Conclusion There may be an association between familial exudative vitreoretinopathy and angle-closure glaucoma as a direct result of a retrolental process or more likely a relative lens-iris pupillary block with a large lens.